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yeast two hybrid

13 novembre 2012

Interleukin-1 stimulation of human endothelial cells to produce granulocyte - macrophage colony-stimulating factor, granulocyte

Endothelial cells is an effective water-soluble products of monocyte-derived hematopoietic growth factor stimulation. Interleukin-1 (IL-1) is released by activated monocytes mediate inflammatory response. We determine whether purified recombinant human...
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13 novembre 2012

Erythropoietin receptor

Erythropoietin receptor ( EpoR) by the the EPOR gene encoding the protein in humans. The EpoR The 59 kDa peptide is a member of the cytokine receptor family. The EpoR pre-existing dimer binding a ligand of the 34 kDa erythropoietin the prime (EPO), to...
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9 novembre 2012

Neuregulin 1 in neural development, synaptic plasticity

Schizophrenia is a very debilitating mental illness that affects 1% of the total population, but it is still poorly understood. Recent studies have found several genes associated with the disease in different groups of people, including those encoding...
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9 novembre 2012

Animal studies on Epo Receptor mutations

The truncated EpoR mice is feasible, which show that the activity of Jak2 is activated in the case of a sufficient basis for erythropoietin support necessary pathway phosphorylation require docking site. EpoR truncati
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9 novembre 2012

Erythroid survival

The EpoR major role in the rescue of a sufficient number of erythroid progenitor cells to cell death . EpoR of Stat5 signal transcription factor GATA-1, induced transcription of pro-survival protein Bcl-xL. In addition, the negative impact of the death...
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7 novembre 2012

Yeast Two-hybrid screening

Two hybrid screening ( also known as the yeast two-hybrid system or precipitation ) is a molecular biology technique for the discovery of protein - protein interactions and protein RNA interaction - Test physical interactions (such as binding between...
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